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正交试验优化管花肉苁蓉水提取工艺

Optimization of Extraction Technology of Cistanche tubulosa by Orthogonal Test

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【作者】 葛继红吴亚东闫波

【Author】 GE Ji-hong,WU Ya-dong,YAN Bo(Dept. of Pharmacy,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

【机构】 新疆医科大学第一附属医院药剂科

【摘要】 目的:优选管花肉苁蓉水提取最佳工艺。方法:以管花肉苁蓉中的苯乙醇苷提取量为检测指标,以料液比、提取时间、提取次数为考察因素,采用正交试验法进行优选。结果:管花肉苁蓉的最佳水提工艺为料液比1∶15,回流提取3次,每次1h。结论:本工艺成本低廉、安全性高、生产周期短、提取率高,对管花肉苁蓉制剂的大生产具有指导意义。

【Abstract】 OBJECTIVE:To optimize the extraction technology of Cistanche tubulosa.METHODS:The extract technology of C.tubulosa was optimized by orthogonal test with solid-liquid ratio,extraction time and extraction times as factors and with the yield of phenylethanoid glycosides as index.RESULTS:The optimal extraction condition for C.tubulosa was as follows:the solid-liquid ratio was 1∶15;the reflux extraction was conducted for 3 times(1 hour each time).CONCLUSION:The optimized technology is characterized by lowcost,good safety,short production cycle and high yield,and it serves as guidance for the macro-production of preparations of C.tubulosa.

  • 【文献出处】 中国药房 ,China Pharmacy , 编辑部邮箱 ,2009年30期
  • 【分类号】R284.2
  • 【被引频次】7
  • 【下载频次】450
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