【摘要】 目的:通过探讨维持性血液透析患者营养状况并探讨骨代谢毒素对营养不良的影响,为营养不良和肾性骨病的治疗提供依据。方法:入选维持性血液透析患者69例,测定指标,①肾性骨病相关毒素,血清甲状旁腺素(PTH)、血钙、磷;②营养学测定,MQSGA、白蛋白、IGF-1、IGF-BP3、人体指数学测量(BSF、TSF、MAC、MAMC);③贫血指标,Hb、HCT、转铁蛋白(TF);④微炎症标志,血清C-反应蛋白(CRP)。结果:血液透析患者营养不良发生率达69.6%;iPTH与MQSGA、ALB、Hb、MAC、MAMC、IGF-1相关性存在统计学意义,P<0.05;钙磷沉积与MQSGA、ALB、Hb、MAC、MAMC相关,P<0.05。结论:维持性血液透析患者营养不良发生率高,PTH、钙磷代谢是影响血液透析患者营养状态、蛋白代谢和贫血的重要因素。更多还原

【Abstract】 Objective:To study the nutrition status of patients in maintenance hemodialysis and how parathyroid hormone affects nutritional status of these patients.Provide evidence for the treatment of malnutrition and renal osteodystrophy.Methods:The determination standard with 69 patients:①Serum PTH,Ca,Pi;②MQSGA,albumin,IGF-1,IGF-BP3,Anthropometric indices biceps skin fold(BSF) ,triceps skin fold(TSF) ,transferrin mid arm circumference(MAC) and mid arm muscle circumference(MAMC) were measured.③Hb,HCT and transferrin;④C-reactive protein.Results:The incidence of malnutrition was 69.6%.There were significantly relationship between PTH and MQSGA,ALB,Hb,MAC,MAMC,IGF-1,P <0.05;It demonstrated significant correlation between deposition of calcium and phosphorus and phosphate product and MQSGA 、 ALB、HB、MAC and MAMC,P<0.05.Conclusion:The incidence of malnutrition of maintained hemodialysis is still high,and we should pay more attention to these patients in clinic work.There is important factor that PTH and calcium and phosphorus metabolism.更多还原