【摘要】 目的探讨糖尿病性视网膜病变(diabetic retinopathy,DRP)中医证候与荧光素眼底血管造影(fundus fluorescein angiography,FFA)表现的相关性。方法以2002年《中药新药治疗糖尿病的临床研究指导原则(试行)》中的糖尿病中医证候诊断标准为蓝本进行改良设计,以主证证候+次证证候+舌脉证候的形式,确定中医证候的证型归属。观察100例西医确诊的DRP患者的中医证候特点,结合其FFA造影改变,统计分析DRP中医证候与FFA造影表现之间的相关性。结果100例DRP患者中阴虚热盛证18例(占18%),湿热困脾证35例(占35%),气阴两虚证23例(占23%),阴阳两虚、血瘀水停证23例(占23%),血瘀脉络证1例(占1%)。在FFA检查中,以新生血管形成这一表现差异具有统计学意义(P<0.05)。结论DRP各中医证型在FFA造影中出现新生血管,以阴阳两虚、血瘀水停证和阴虚热盛证多见。更多还原

【Abstract】 OBJECTIVE To study the relation between TCM syndrome patterns and fundus fluorescein angiography (FFA) performance in diabetic retinopathy (DR). METHODS The improved 2002 TCM Guiding Principles for Clinical Research on Diabetes Treatment (Trial) were used as the guideline. With the main syndrome, secondary syndrome and tongue and pulse syndrome, the relation between TCM syndrome patterns and FFA performance of 100 DR patients was statistically analyzed. RESULTS Among 100 cases, 18 were Yinxuresheng syndromes, (阴虚热盛)(18%), 35 were Shirekunpi syndromes(湿热困脾) (35%), 23 were Qiyinliangxu syndromes (气阴两虚)(23%), 23 were Yinyangliangxu syndromes and Xueyushuiting syndromes (阴阳两虚, 血瘀水停)(23%), 1 was Xueyumailuo syndrome (血瘀脉络)(1%). By contrast with the performance of the FFA, the formation of new blood vessels showed statistical differences (P<0.05). CONCLUSIONS Yinyangliangxu,Xueyushuiting and Yinxuresheng syndrome patterns were easy to appear neovascularization in the FFA of DR.更多还原