【摘要】 目的比较帕罗西汀与氟西汀对抑郁症的疗效和不良反应。方法将60例符合中国精神障碍分类与诊断标准第3版抑郁发作诊断标准的患者随机分为帕罗西汀组与氟西汀组。疗程6周,剂量均用20mg/日,口服。采用汉密尔顿抑郁量表(HAMD)评定疗效。用副反应量表(TESS)评定不良反应。结果帕罗西汀组与氟西汀组有效率分别是83.3%和76.7%,两者疗效相仿。HAMD评定帕罗西汀组治疗1周即显著下降,氟西汀组治疗4周时显著下降。帕罗西汀反应较好。结论帕罗西汀是一种起效更快,副作用更小,疗效可靠的新型抗抑郁药。更多还原

【Abstract】 Objective To compare the curative effects and the adverse effects between Paroxetine and Fluoxetine.Methods According to CCMD-3,there were 60 samples from patients of depression who were stochastically group in two sets.They were treated by Paroxetine and Fluoxetine in 6 weeks with dose 20mg/d.Results The effective power of Paroxetine is 83.3%.The effective power of Fluoxetine is 76.7%.According to HAMD,the curative effects of Paroxetine are obvious in 1 week.Fluoxetine’s are in 4 weeks.Paroxetine is better.Conclusion Paroxetine’s adverse effects are less.Curative effects of Paroxetine are better than neotype antidepressants.更多还原