【摘要】 目的:观察次声作用对大鼠精子质量的影响,初步探讨次声对雄性生殖系统的作用机制。方法:成年雄性SD大鼠分别经8Hz、90dB或130dB的次声作用l、7、14、2ld(2h/d),取副睾检测其精子计数、畸形率和活动率,取同侧睾丸检测谷胱甘肽过氧化物酶(GSH-Px)和丙二醛(MDA)水平。结果:8Hz、90dB和130dB次声作用组随次声作用时间延长,精子质量下降,MDA水平升高,GSH-Px下降。在同一时点上,130dB次声作用组的各项指标与90dB组相比,变化更为显著。结论:次声对睾丸的生物学效应与其作用参数有关,抗氧化系统失衡可能是该效应的发生机制。更多还原

【Abstract】 AIM:To observe the effects of infrasound on sperm quality and explore some underlying mechanisms. METHODS: Adult male SD rats were exposed to infrasound of 8 Hz at 90 dB or 130 dB for 1,7,14 or 21 d(2 h/d), whose epididymises were obtained for sperm count, abnormity and activity ratio inspection and whose testes for GSH-Px and MDA inspection. RESULTS: With prolonged exposure, sperm quality and GSH-Px in 90 dB and 130 dB groups decreased, while MDA increased, and at the same time point, the indexes of 130 dB groups changed more profoundly than those in 90 dB groups. CONCLUSION: Biological effect of infrasound on testes depends on the exposure parameters. The mechanisms of which could be unbalanced antioxidant system induced by infrasonic exposure.更多还原