【摘要】 目的观察肝癌介入治疗后超声造影(CEUS)表现,并与增强CT(NCCT)比较,评估超声引导下瘤内注射无水乙醇治疗肝癌疗效价值。方法应用声诺维对比剂,使用低机械指数成像技术,对23例肝癌患者(共34个结节),在超声引导下经皮穿刺无水乙醇注射(PEI)治疗5次,CEUS显像将病灶分为有增强和无增强两类。结果介入治疗后,CEUS显示27个病灶无增强为79.4%,7个病灶动脉相部分增强20.6%,NCCT显示29个病灶无强化为85.3%,5个病灶部分强化,肿瘤残留14.7%;实时谐波CEUS评估肝恶性肿瘤介入治疗疗效的敏感性为87.8%,特异性为78.4%,符合率为79.4%,同NCCT比较CEUS诊断的敏感性更高,不受沉积碘油的影响。结论 CEUS可以作为肝脏恶性肿瘤介入治疗疗效评估的可靠方法,与NCCT比较具有相同价值,且对于经碘油栓塞的病人优于NCCT。更多还原

【Abstract】 Objective To observe the performance of CEUS in liver cancer after interventional therapy compared with that of NCCT,to assess the therapeutic effect of injecting absolute alcohol into liver cancer with ultrasonic guidance.Methods SonoVue contrast agent and low-mechanical index imaging technology were used.Twenty-three patients with liver cancer( 34 nodules) underwent percutaneous ethanol injection( PEI) under the guide of ultrasound for five times.The lesions were divided into two categories according to their performance of CEUS imaging,the enhanced lesions and the non-enhanced lesions.Results After interventional therapy,CEUS showed that 27 lesions had no enhancemant (79.4%) and 7 lesions were enhanced partialy in artery phase.NCCT showed that 29 lesions had no enhancemant ( 85.3%),five lesions were enhanced partialy due to residual tumor( 14.7% ).The real-time harmonic wave CEUS was used to evaluate the therapeutic effect of the interventional therapy,and the sensitivity,specificity and coincidence were 87.8%,78.4% and 79.4% respectively.The sensitivity of CEUS was higher than that of NCCT without the impact of depositive iodized oil.Conclusion CEUS could be used as reliable method to evaluate the therapeutic effect of interventional therapy for liver cancer.It has the same value compared with NCCT,but is better than NCCT for the patients using iodized oil embolization.更多还原