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氧化锌纳米线尿酸氧化酶固定性能(英文)

Uricase immobilized on ZnO nanowires for uric acid detection by quartz crystal microbalance

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【作者】 王小华张健朱自强朱建中

【Author】 WANG Xiao-hua,ZHANG Jian,ZHU Zi-qiang,ZHU Jian-zhong(Department of Electrical Engineering,East China Normal University,3663 North Zhongshan Road,Shanghai 200062,China)

【机构】 华东师范大学电子工程系

【摘要】 本文利用石英晶体微天平研究了氧化锌纳米线对尿酸氧化酶的固定性能和作为尿酸传感器的应用。本文在PBS溶液中对尿酸氧化酶进行固定,并且利用固定的传感器作为尿酸传感器,能检测浓度范围从5.0×10-6到8×10-5molL-1的尿酸含量,所有结果都说明氧化锌纳米线是一种很好的生物传感器的材料。

【Abstract】 A uric acid(UA)biosensor based on uricase immobilized on ZnO nanowires was studied by quartz crystal microbalance(QCM).The stability of immobilized uricase was studied.Uricase was immobilized in PBS solution.And the frequency response showed a linear dependence on the uric acid concentration ranging from 5.0 × 10-6 to 8 × 10-5 molL-1.The results indicated one-dimensional ZnO structure is a good material for biosensor application.

【基金】 National Nature Science Foundation(No.60672002)
  • 【文献出处】 功能材料与器件学报 ,Journal of Functional Materials and Devices , 编辑部邮箱 ,2009年02期
  • 【分类号】TB383.1
  • 【被引频次】1
  • 【下载频次】141
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