【摘要】 目的:探讨了尖锐湿疣患者治疗前后血清TNF-α、hs-CRP和GM-CSF水平的变化及意义。方法:应用放射免疫分析和免疫比浊法对62例尖锐湿疣患者进行了血清TNF-α、hs-CRP和GM-CSF检测,并与35名正常健康人作比较。结果:在治疗前尖锐湿疣患者TNF-α、hs-CRP和GM-CSF水平均非常显著地高于正常人组(P<0.01)。经3个月治疗后血清TNF-α、hs-CRP和GM-CSF水平与正常人组比较无显著性差异(P>0.05)。患者组治疗前后血清TNF-α、hs-CRP和GM-CSF水平也有显著性差异(P<0.01)。结论:检测尖锐湿疣患者血清TNF-α、hs-CRP和GM-CSF水平的变化对疾病的治疗、预后观察有重要的临床价值。更多还原

【Abstract】 Objective To explore the significance of changes of serum TNF-α,hs-CRP and GM-CSF levels after treatment in patients with condyloma acuminatum.Methods Serum levels of GM-CSF(with RIA)and TNF-α,hs-CRP levels(with immuno-turbidimetry method)were measured both before and after treatment in 62 patients with condyloma acuminatum and 35 controls.Results Before treatment,the serum TNF-α,hs-CRP and GM-CSF levels in the patients were significantly higher than those in controls(P<0.01).After treatment for 3 months,the levels were not significantly different from those in controls(P>0.05).Serum TNF-α,hs-CRP and GM-CSF lends in patients before the treatment were significantly higher than those after treatment(P<0.01).Conclusion The levels of serum TNF-α,hs-CRP and GM-CSF increased significantly in patients with condyloma acuminatum especially in those advanced cases.更多还原