节点文献
正交试验法优选前列宁颗粒剂的提取工艺
Optimization of the Extraction Process of Qianliening Granules by Orthogonal Test
【摘要】 [目的]筛选和优化前列宁颗粒剂提取工艺。[方法]采用正交设计法,以水醇两组提取物中浸膏得率、有效成分分别为大黄酸和黄芪甲苷提取率为指标,确定提取参数。[结果]确定黄芪等药组水提工艺为10倍量水,煎煮3次,每次1.5h;大黄等药醇提组工艺为6倍量60%乙醇,提取2次,分别为2.0、1.5h。[结论]前列宁颗粒剂提取工艺稳定,可行。
【Abstract】 [Objective]To filter and optimize extractive technology of Qianliening granules.[Methods]The optimization extractive technology of Qianliening granules was investigated using orthogonal design with the availability component extracting from the drug as the index.[Results]The optimal condition for the extraction of Radix Astragali group was 10 folds amount of water,3 times,1.5 hours each time.The optimal condition for the extraction of Rheum officinal Baill.group was 6 folds amount of 60% alcohol,2 times,two hours and 1.5 hours each time.[Conclusion]The optimized extractive technology is scientific and efficient.
【Key words】 Qianliening Granules; Rhein; Astragaloside IV; extractive technology; orthogonal design;
- 【文献出处】 浙江中医药大学学报 ,Journal of Zhejiang University of Traditional Chinese Medicine , 编辑部邮箱 ,2009年04期
- 【分类号】TQ461
- 【被引频次】9
- 【下载频次】116