【摘要】 目的探讨深板层角膜移植术治疗角膜溃疡的临床效果。方法采用甘油冷保存的角膜组织对22例(22眼)药物治疗无效的角膜溃疡行深角膜板层移植术。真菌性角膜溃疡16眼,病毒性角膜溃疡4眼,热烧伤引起的角膜溃疡2眼。其中角膜溃疡穿孔10眼,术中行双板层移植,前房注气。结果随访5～24个月,21眼角膜植片存活,溃疡治愈率95.45%,1眼术后原发病复发,2眼术后移植片血管化,19眼角膜半透明,视力提高。结论对药物治疗无效的角膜溃疡,及时应用甘油冷保存的角膜组织行深板层角膜移植术,可以控制炎症,恢复部分视力。更多还原

【Abstract】 Objective To investigate the clinical effect of deep lamellar keratoplasty for corneal ulcer.Methods Deep lamellar keratoplasty was performed on 22 eyes of 22 cases of corneal ulcer with drug refractory,16 eyes with mycotic corneal ulcer,4 eyes with herpes simplex keratitis,2 eyes with thermal burn;10 cases with perforated corneal ulcer were treated with deep lamellar keratoplasty combined with interlamellar padding.Results All patients were followed up for 5 to 24 months,grafts of 21 cases were survivorship(95.45%),1cases had recrudescence;grafts of 2 cases turned vascularize,grafts of 19 cases remained clear,and visual acuity improved.Conclusion Deep lamellar keratoplasty is valuable in the management of corneal ulcer with drug refractory.It can succeed curing infection,achieving a useful visual acuity.更多还原