节点文献
脑缺血/缺氧预适应相关蛋白质及其功能研究进展
Advance in Research on Proteins Related with Brain Ischemia/Hypoxia Preconditioning and Their Functions(review)
【摘要】 脑缺血/缺氧预适应(I/HPC)是机体抗缺血缺氧的一种内源性保护现象。研究显示,低氧诱导因子-1(HIF-1)、热休克蛋白(HSPs)、促红细胞生成素(EPO)、Bcl-2家族、降钙素基因相关肽(CGRP)等多种蛋白质参与脑I/HPC,作者就这些蛋白质的功能及参与I/HPC的机制作一阐述。
【Abstract】 Brain ischemia/hypoxia preconditioning(I/HPC) is one kind of endocardial protective phenomenon by organism against blood and oxygen deficit.Researches discovered various proteins such as hypoxic inducible factor-1(HIF-1),heat shock proteins(HSPs),erythropoietin(EPO),Bcl-2 family,calcitoningene related peptide(CGRP) and so on participated in brain I/HPC.This essay explains function and participating I/HPC mechanism of these proteins.
【关键词】 脑缺血/缺氧预适应;
低氧诱导因子-1;
热休克蛋白;
促红细胞生成素;
功能;
综述;
【Key words】 brain ischemia/hypoxia preconditioning; hypoxic inducible factor-1; heat shock protein; erythropoietin; function; review;
【Key words】 brain ischemia/hypoxia preconditioning; hypoxic inducible factor-1; heat shock protein; erythropoietin; function; review;
- 【文献出处】 中国康复理论与实践 ,Chinese Journal of Rehabilitation Theory and Practice , 编辑部邮箱 ,2008年10期
- 【分类号】R363
- 【被引频次】3
- 【下载频次】366