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广州地区老年患者社区获得性下呼吸道感染病原学调查
Etiology of Community-acquired Lower Respiratory Tract Infections in Elderly in Guangzhou Area
【摘要】 目的调查广州市老年患者社区获得性下呼吸道感染的病原体分布,为其经验治疗提供科学依据。方法应用VITEK-60或PHOENIX-100微生物自动鉴定系统进行病原菌鉴定,血清学及聚合酶链反应技术检测肺炎支原体、肺炎衣原体和嗜肺军团菌。结果107例次广州市老年患者社区获得性下呼吸道感染中,病原体阳性率为51.4%,其中,病原菌68.5%,非典型病原体31.6%,感染单一病原体以肺炎支原体最常见,其次为嗜血菌属。结论针对老年患者社区获得性下呼吸道感染的经验治疗,在考虑病原菌的同时,不能忽视非典型病原体的存在。
【Abstract】 OBJECTIVE To investigate the pathogenic causes of lower respiratory tract infections(LRTIs) in the elderly in Guangzhou area.METHODS Pathogens obtained from 107 patients with LRTIs were performed by multiple diagnostic tools that including bacterial culture,PCR and specific immunological assays.RESULTS A bacterial cause was established in 42(68.5%) and an atypical pathogen cause in 25(31.6%) of the 107 patients.Mycoplasma pneumoniae and Haemophilus influenzae remained the most important pathogens for LRTIs.CONCLUSIONS In the prescription of antibiotics in the elderly with LRTIs,not only bacteria but also atypical pathogens should be taken into account.
【Key words】 Elderly; Community-acquired lower respiratory tract infections; Etiology; Pathogens;
- 【文献出处】 中华医院感染学杂志 ,Chinese Journal of Nosocomiology , 编辑部邮箱 ,2008年11期
- 【分类号】R56
- 【被引频次】6
- 【下载频次】85