【摘要】 目的探讨2型糖尿病患者病情与足背动脉血管病变的相关性。方法对临床确诊的97例2型糖尿病患者与46例同期住院的非2型糖尿病患者,行常规超声检查观察足背动脉,测量血管内膜-中层厚度,观察内膜面有无毛糙、斑块,血管腔有无狭窄或闭塞;行彩色多普勒血流成像(CDFI)观察血管腔内彩色血流信号有无充盈缺损及血流频谱形态。结果2型糖尿病患者足背动脉血管内中膜均有不同程度的改变,合并有高脂血症和高血压的患者足背动脉血管和大血管分叉处均有明显病变,而单项血糖增高患者除足背动脉血管内膜及中膜血管病变外,大血管分叉处病变程度相对较轻。2型糖尿病患者足背动脉血管狭窄(6.19%),闭塞(2.06%)的发生率明显高于对照组(P<0.01)。结论2型糖尿病患者足背动脉血管内膜及中膜病变程度与病情有明显相关性。彩色多普勒超声检测足背动脉血管可评估2型糖尿病患者的病情及预后,对早期诊断、预防及治疗具有重要的临床应用价值。更多还原

【Abstract】 Objective To evaluate the correlation between lesions of dorsal artery of foot and type 2 diabetes on CDFI.Methods Dorsal artery of foot was examinated in 97 cases with type 2 diabetes and 46 cases without diabetes mellitus.Results There were variable changes in intima-media of dorsal artery of foot in type 2 diabetes patients.And the patients with hyperlipidemia and hypertension showed serious lesions in the dorsal artery of foot and bifurcation of the blood vessel.Simple arteriosclerosis showed not only lesions in intima-media of dorsal artery of foot but also relative mild lesions in bifurcation of the blood vessel.Blood vessel lesion incidence in type 2 diabetes was significantly higher than that of the control group(P<0.01).Conclusions There was a significant correlation between lesions of dorsal artery of foot and type 2 diabetes patient’s condition.CDFI is an effective method in evaluating patient’s condition,degree and prognosis of type 2 diabetes,and has an important clinical value in early diagnosis,prognosis and treatment.Simple arteriosclerosis showed focal lesions in bifurcation of the blood vessel while dorsal artery of foot showed relatively mild lesions.更多还原