【摘要】 目的:探讨青少年时期的体力活动对绝经后骨质疏松症发病的影响。方法:选择2007年2月～2008年2月在我院就诊患者134例,分为病例组和对照组,每组67例,调查两组青少年时期的体力活动情况(包括参加专项训练情况和是否爱好体育活动),同时调查人口社会学特征,月经史、婚育史、目前体力活动水平等。结果:对照组和病例组年龄、职业、文化程度、补钙、月经婚育史和母乳喂养史等方面比较,差异无统计学意义(P>0.05)。青少年时期爱好体育活动,经常进行负重或冲击性活动可以减少绝经后骨质疏松症发病危险(OR=0.208,95%CI:0.100～0.432;OR=0.207,95%CI:0.099～0.430);对目前体力活动水平、生育期使用避孕药、绝经后使用激素替代等混杂因素校正后,青少年时期爱好体育活动对绝经后骨质疏松症发病危险的影响仍然存在(OR=0.237,95%CI:0.081～0.693)。但病例组和对照组青少年时期参加专项训练情况比较,差异无统计学意义(P>0.05)。结论:青少年时期体力活动是绝经后骨质疏松症的保护因素,可降低发病危险。更多还原

【Abstract】 Objective:To elucidate the association between the level of physical activities(PA)in the developmental phase with the risk of osteoporosis in postmenopausal(PMO)women.Methods:134 patients in this hospital were averagely divided into cases and control groups.Respondents were asked about the situation of PA in the developmental phase.The information about age,occupation,education,and menstrual history,childbearing history,breast feeding history,etc were also obtained in an interviewer-adminstered questionnaire.Results:The cases group and controls group had no difference in age,occupation,and education level,etc(P>0.05).The exercise,and participating in weight-bearing or compact exercise during anaplasis were beneficial to decrease the risk of PMO(OR=0.208,95%CI:0.100~0.432;OR=0.207,95%CI:0.099~0.430).After adjusted by other confounded factors,the effect still existed(OR=0.237,95%CI:0.081~0.693).But there was no significant difference in participation in special training in adolescence period between two groups(P>0.05).Conclusion:The level of physical activities during anaplasis may be associated with the risk of osteoporosis in postmenopausal women.更多还原