【摘要】 目的:建立太子参HPLC-MS指纹图谱分析方法,评价不同产地太子参药材的质量。方法:用HPLC-MS联用技术对不同产地太子参进行分析,测定其总离子流指纹图谱,确定共有峰,并对部分色谱峰进行了初步归属。结果:初步建立了以10个共有峰为特征指纹信息的HPLC-MS指纹图谱;发现少数产地太子参HPLC-MS指纹图谱差异显著。结论:方法准确可靠,重现性好,可作为太子参内在质量评价的依据。更多还原

【Abstract】 AIM:To establish the analytical method for the fingerprint of Radix Pseudostellariae by HPLC-MS and to estimate the quality of Radix Pseudostellariae from different habitats. METHODS: Radix Pseudostellariae from different habitats were analyzed and the total ion current(TIC) chromatographic fingerprint were determined by HPLC-MS.Some characteristic peaks were identified preliminarily based on the MS spectra and literature data. RESULTS: HPLC-MS fingerprint of 10 main peaks was established preliminarily.It was found that a small number of samples differed from others obviously. CONCLUSION: The method is reliable,accurate and can be used for quality control of Radix Pseudostellariae.更多还原