【摘要】 [目的]观察恶性梗阻性黄疸患者于经皮肝穿刺胆道造影及引流术(PTCD)术后血清总胆汁酸(TBA)、总胆红素(TBL)及直接胆红素(DBL)的变化。[方法]122例恶性梗阻性黄疸患者PTCD术前1d及术后第3d至4周内作TBA、TBL、DBL检测。[结果]PTCD术前TBA(131.8±76.6μmol/L)与TBL(416.0±127.5μmol/L)、DBL(300.4±86.9μmol/L)有良好相关性(r值:0.358、0.379,P<0.05);术后3dTBA下降明显(15.9±22.6μmol/L),与术前(131.8±76.6μmol/L)比较有显著性差异(P<0.01)。[结论]血TBA可作为检验PTCD术后黄疸引流是否有效的可靠指标。更多还原

【Abstract】 [Purpose] To study the alteration of serum total bile acid(TBA),total bilirubin(TBL) and direct bilirubin(DBL) after percutaneous transhepatic cholangiography and drainage(PTCD) for malignant obstructive jaundice patients. [Methods] TBA,TBL and DBL were detected 1 day before and 3 days to 4 weeks after PTCD. [Results] TBA (131.8±76.6μmol/L) closely correlated with TBL (416.0±217.5μmol/L) and DBL (300.4±86.9μmol/L) before PTCD(r:0.358,0.379,P<0.05). TBA decreased significantly at 3d after PTCD (15.9±22.6μmol/L),with significant,descending rate of TBA difference compared with that before PTCD(131.8±76.6μmol/L)(P<0.01). [Conclusion] TBA can be used as a reliable indicator to test whether jaundice draining is effective.更多还原