【摘要】 目的:观察小剂量糖皮质激素辅助治疗小儿大叶受累的肺炎支原体肺炎(MPP)的疗效。方法:将MPP胸部X线(胸片)表现为大叶受累的患儿64例随机分为2组,均给予常规治疗,治疗组在此基础上给予地塞米松[0.2mg/(kg.d)]静滴,连用3～5d,对比观察两组退热、胸片大片阴影消退时间、C-反应蛋白(CRP)变化及住院时间。结果:治疗组发热持续时间、胸片大片影消退时间及住院时间明显少于对照组(P<0.05),且CRP水平随病情好转显著下降,差异有统计学意义(P<0.05)。结论:小剂量激素辅助治疗小儿大叶受累的MPP,可有效的缓解临床症状,缩短发热和胸部大片影消退时间,从而减少住院天数。更多还原

【Abstract】 Objective: To evaluate the effectiveness of low doses of glucocorticoid in the assistance treatment of mycoplasmal pneumoniae lobar pneumonia in children.Methods: Sixty-four cases of mycoplasmal pneumonia were divided into two groups according to chest X rays manifested of lobal pneumonia. Thirty-two cases in control group were given routine treatment and thirty-two cases in observation group were add the dexamethasone intravenously for 3～5 days. The level of serum c-reactive protein(CRP) , duration of fever,regression of lobar shadow and hospital time of two groups were observed. Results: There were significant differences between the two groups in duration of fever, regression of lobar shadow and hospital time(P<0.05). The level of serum CRP decreased with the restore of disease. Conclusion: Adjunctive therapy with low doses of glucocorticoid in treating mycoplasmal lobar pneumonia could effectively alleviate the clinical symptoms,decrease the duration of fever restore of lobar shadow,and reduce the hospital time.更多还原