【摘要】 目的探讨降钙素与肺癌发生骨转移的关系。方法肺癌发生骨转移及未发生骨转移患者各20例,健康对照者20例。用化学发光法测定其血清降钙素浓度。随访0.5~1 a。结果有骨转移者的血清降钙素[(235.0±102.1)pg/ml]明显高于无骨转移者[(141.0±99.1)pg/ml]和健康对照者[(89.0±87.0)pg/ml],P<0.01。结论血清降钙素可作为肺癌早期预测骨转移的指标,并有助于对肺癌骨转移患者进行随访和监测。血清降钙素低于正常值,发生骨转移的可能性相当低;高于正常值,则发生骨转移的可能性较大。更多还原

【Abstract】 Objective To detect the correlation between serum calcitonin and early bone metastases of lung cancer.MethodsA chemiluminescence was employed for determination of serum calcitonin concentrations.Lung cancer patients with(20 cases) or without(20 cases) bone metastases and 20 healthy controls evaluated and followed up for 6 months to one year.ResultsCalcitonin serum concentrations in patients with bone metastases(235.0 pg/ml±102.1 pg/ml) were higher than those in patients without bone metastases(141.0 pg/ml±99.1 pg/ml) and in healthy controls(89.0 pg/ml±87.0 pg/ml).The differences were significant(P<0.01).ConclusionsSerum calcitonin could be a good indicator for early diagnosis of bone metastases in lung cancer patients,and it could be helpful in the follow-up and in monitoring for bone metastases of lung cancer.A normal result of calcitonin indicates a very low probability of bone metastases,while high value calcitonin indicates a high possibility of bone metastases.更多还原