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短暂性脑缺血发作发展至脑梗死危险因素分析
Analysis of risk factors associated with cerebral infarction due to transient ischemia
【摘要】 目的探讨短暂性脑缺血发作(TIA)发展至脑梗死的危险因素。方法对144例TIA患者的临床资料进行分析。结果144例患者中50例(34.7%)发生了脑梗死;其中椎-基底动脉系统TIA20例中11例(55.0%)发生脑梗死;颈内动脉系统TIA118例中37例(31.4%)发生脑梗死;两个系统脑梗死的发生率差异有显著性(P<0.05),78%的脑梗死发生在TIA后1h内,5例死于脑梗死;TIA发作持续>30min、24h内>3次发作以及首次发作后24h或发作>5次开始治疗的患者发生脑梗死的危险性显著增高(P<0.05~0.01),发生脑梗死的TIA患者血压、血糖、血胆固醇显著增高(均P<0.05)。结论患者TIA发作持续久、次数多、未及时治疗,尤其伴有高血压、高血糖、高脂血症者短期内发生脑梗死的危险性较高。
【Abstract】 Objective To discuss the risk factors for cerebral infarction resulting from transient ischemic attack(TIA).Methods The clinical data of 144 hospitalized patients with TIA were evaluated.Results There 50 patients(34.7%) suffered from cerebral infarction(CI) following the onset of TIA in 144 patients.There 11 cases with CI resulted from vertebra-basilar artery system,37 cases resulted from internal carotid artery system.There was significantly different in two artery systems(P<0.05).About 78% of them occurred within l month after the first attack,5 cases died of CI.The risks of cerebral infarction were siginificantly increased in the patients whose syndromes lasted over 30 min,the patients with 3 attacks within 24 h,the patients treated beyond 24 h of syndrome onset,or the treated paticnts with 5 attacks or more(P<0.05~0.01).The high blood pressure,hyperglycemia and hyperlipidemia often occurred to the paticnts with CI(all(P<0.05).Conclusion There is high danger for patients to develop CIif patients with TIA lasted for a long time,or with frequent attacks,or treatment is not yet in time,especially those accompanied with high blood pressrre,hyperglycaemia and hyperlipoidemia.
- 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2008年02期
- 【分类号】R743
- 【被引频次】2
- 【下载频次】125