【摘要】 以1-溴-3-氯丙烷和二甲亚砜为原料,四氢呋喃为溶齐,在氢化钠的作用下成功合成了1-氯-4-甲基亚磺酰基丁烷,其工艺条件为:氢化钠与1-溴-3-氯丙烷的物质的量之比为1:1.3,反应温度为-40℃,反应时间1 h,产率为63.5%。经红外、核磁共振表征确定了该化合物的结构。更多还原

【Abstract】 1-chloro-4-methylsulfinyl-butane was synthesized successfully form 1-bromo-3-chloropropane and dimethyl sulfoxide in the presence of sodium hydride in tetrahydrofuran.the reaction conditions are as follows:sodium hydride:1-bromo-3-chloropropane=1:1.3(mol);reaction temperature,-40 ℃;reaction time,1 h.Its yield is 63.5%.Its structure is characterized and confirmed by IR,1H-NMR.更多还原