【摘要】 目的探讨非侵袭性脑电图在难治性癫痫术前定位中的价值以及发作期与发作间期异常放电对定位的作用。方法回顾性分析行外科致痫灶切除并取得EngelⅠ治疗结果的难治性癫痫患者40例。所有患者均经过严格的术前评估,包括临床发作表现、脑电图检查、影像学检查以及神经心理检查,术中采用皮层脑电图监测切除范围。重点分析头皮脑电图结果的定位意义。结果①非侵袭性脑电图经过合理操作即规范化脑电图检查法明显提高了异常放电的检出率,脑电图定位与影像学病灶并不完全吻合;②发作期异常放电的定侧定位的准确率明显高于发作间期异常放电;③发作间期异常放电的检出率明显高于发作期。结论非侵袭性脑电图的规范性操作对难治性癫痫术前定位具有不可替代的作用,发作期与发作间期异常放电对定侧定位均有较高价值。更多还原

【Abstract】 Objective To investigate the value of non-invasive electroencephalography(EEG) and the role of interictal epileptiform discharges and ictal epileptiform discharges on surgery location for refractory epilepsy.Methods Forty cases with refractory epilepsy who received surgery and got the therapeutic result of EngelⅠwere studied retrospectively.A rigorous preoperative appraisal was adopted,including the clinical performance of the attack,the results of electroencephalo-graphy,imageology and neuropsychologic examination.Electrocorticogram was applied in operation for monitoring the range of resection.Results ①Normative EEG method could significantly increased the positive discovery of epileptic wave compared with common EEG in our group.②Ictal epileptiform discharges had a high accuracy rating in locating.③Interictal epileptiform discharges had a high detection rate.Conclusion If we had a normative work in EEG checking,EEG would Perform the all-important role in surgery location of refractory epilepsy.Meanwhile,interictal epileptiform discharges and ictal epileptiform discharges had identically significant contribution in surgery location of refractory epilepsy.更多还原