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消银颗粒治疗血虚风燥型白疕临床观察及对肿瘤坏死因子的影响

Efficacy and Influence of TNF-α Using Xiaoyin Granules to Treat Baibi of Blood asthenia and Wind-dry

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【作者】 钟金宝梁艳华李仰琪何伟强李燕红梁燕梅

【Author】 ZHONG Jin-bao,LIANG Yan-hua,LI Yang-qi,HE Wei-qiang,LI Yan-hong,LIANG Yan-mei(Guangzhou Institute of Dermatology and Veneroloy,GuangZhou 510095,Guangdong,China)

【机构】 广州市皮肤性病防治所

【摘要】 目的:观察"消银颗粒"治疗血虚风燥型白疕的疗效及探讨其作用机制。方法:随机将120例白疕患者分为治疗组与对照组,治疗组内服"消银颗粒"治疗,对照组内服迪银片;检测患者治疗前后肿瘤坏死因子(TNF-α)的水平,并和正常对照组比较。两组均以1个月为1个疗程,2个疗程后进行疗效判定。结果:治疗组60例基本痊愈37例,显效11例,有效7例,无效5例,对照组60例基本痊愈24例,显效13例,有效8例,无效15例,治疗组基本痊愈率及总有效率均高于对照组(P<0.05)。两组治疗后TNF-α较治疗前降低,治疗组优于对照组(P<0.05)。结论:"消银颗粒"是一种治疗银屑病的有效方法,可能通过降低患者血清TNF-α水平起作用。

【Abstract】 Objective:To observe the therapeutic effects of Xiaoyin Granules treatment on Baibi of blood asthenia and wind-dry,and reseach active mechanism.Methods:One hundred and twenty patients with Baibi were randomly divided into two groups,treated with single blind method.The treatment group were treated by Xiaoyin Granules;and the control group by Diyin tablets;detect the serum levels of TNF-α in the patients with psoriasis at treatment beginning and end,and compare with the normal control group.One courses of the treatment is one month,After two course of the treatment decide the healing effect.Result:60 cases in the test group,37 cases were cured,11 cases markedly effective,7 cases effective,5 cases ineffective,60 cases in the control group,24 cases were cured,13 cases markedly effective,8 cases effective,15 cases ineffective,with significant difference between the two groups in total effective rate(P<0.05).The TNF-α in the two groups after treatment decreased,and the test group is superior the control group(P<0.05).Conclusion:This study indicated that Xiaoyin Granules is a effective method for psoriasis,and it can play a role through reducing the serum levels of TNF-α in the patients with psoriasis.

【关键词】 白疕消银颗粒TNF-α
【Key words】 BaibiXiaoyin GranulesTNF-α
【基金】 2006年广州市中医药中西医结合科研资助项目(2006A29)
  • 【文献出处】 辽宁中医杂志 ,Liaoning Journal of Traditional Chinese Medicine , 编辑部邮箱 ,2008年12期
  • 【分类号】R275.9
  • 【被引频次】5
  • 【下载频次】128
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