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Rh阴性血型筛查及其抗体检测的临床意义
Clinical Significance of RhD-negative Screening and the Detection of its Antibody
【摘要】 目的对Rh阴性血型的筛查及其抗体的检测,为临床预防溶血性输血反应和新生儿溶血病的发生提供实验室依据.方法用抗D(IgM)血型定型试剂对13 208例受检者进行Rh血型鉴定.通过盐水法、聚凝胺法、间接抗人球蛋白法检测Rh阴性血中的抗体.结果13 208例受检者中,检出Rh(D)阴性75例,其中检出Rh血型免疫性抗体5例.结论常规对Rh阴性血型进行筛查及其抗体的检测,对预防溶血性输血反应,新生儿溶血病的发生及安全输血有着重要的临床意义.
【Abstract】 Objective To provide laboratory proof for the precaution of hemolytic transfusion reaction and hemolytic disease of newborn by RhD-negative screening and the detection of its antibody.Methods The Rh(D) blood types were detected by anti-IgD(IgM) blood grouping reagents,and the antibodies were detected by Saline method,Polybrene test and Indirect antiglobulin test.Results 75 samples Rh(D)-negative were detected in 13 208 samples,including 5 samples Rh(D) blood type immunity antibody.Conclusion It is very important for Rh(D)-negative screening and the detection of its antibody to prevent hemolytic transfusion reaction and hemolytic disease of newborn and blood transfusion in safety by conventional approach.
【Key words】 Rh(D)-negative; Antibody; Hemolytic transfusion reaction; HDN;
- 【文献出处】 昆明医学院学报 ,Journal of Kunming Medical University , 编辑部邮箱 ,2008年06期
- 【分类号】R446.6
- 【被引频次】3
- 【下载频次】195