【摘要】 目的研究单纯肥胖或代谢综合征(metabolic syndrome,MS)患者血清抵抗素(resistin)的水平与健康对照者比较是否有差别,从而确定血清resistin与单纯肥胖或代谢综合征是否相关。方法健康对照者54例,单纯肥胖60例,均为2005~2006年在我院进行体检的志愿者;代谢综合征患者58例,为2005~2006年在我院就诊的符合IDF关于代谢综合征诊断标准的患者,由专人记录并测定受试者的年龄、性别、身高、体重、腰围、臀围及血压等临床资料。采集受试者外周静脉血,测定空腹血糖、血脂r、esistin、胰岛素原(PI)、真胰岛素(TI)、胰高血糖素,并计算BMI、WHR、BF、PI/TI、HOMA-IR指数。结果正常人、单纯肥胖、代谢综合征患者血清中resistin的水平无统计学差异。结论血清resistin水平可能不是联系肥胖、胰岛素抵抗及代谢综合征的主要纽带。更多还原

【Abstract】 Objective To research the relationship between serum resistin and isolated-obesity or metabolic syndrome(MS).MethodsFifty-four healthy subjects and sixty patients with isolated-obesity came from volunteers who accepted health examination from 2005 to 2006 in our hospital.According to IDF standards,fifty-eight MS in our hospital during 2005～2006 took part in our study.Clinical information was recorded by special person.Fasting glucose,lipid,resistin,PI,TI,glucagon were measured and BMI,WHR,BF,PI/TI,HOMA-IR were tested.ResultsNo significant difference was found among healthy persons and patients with isolated-obesity or MS.ConclusionSerum level of resistin may not be related to obesity,insulin-resistance or MS.更多还原