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乌鲁木齐高考学生输血传播病毒感染的比较分析

Comparative Analysis of TTV Infection in College Candidates in Urumqi

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【作者】 韩月宁王亚男雷新莉马秀敏丁剑冰曹春宝贾海英阿曼古丽·牙生吴曰铭

【Author】 HAN Yue-ning1,WANG Ya-nan2,LEI Xin-li3,MA Xiu-min2,DING Jian-bing2,CAO Chun-bao2,JIA Hai-ying2,Amanguly YASEN4,WU Yue-min1(1.The Center for Disease Control and Prevention of Xinjiang Uygur Autonomous Region,Urumqi,Xinjiang 830002,China;2.Xinjiang Medical University,Urumqi,Xinjiang 830054,China;3.Urumqi Traditional Chinese Medicine Hospital;4.Specialized Hepatic Hospital of The First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830054,China)

【机构】 新疆维吾尔自治区疾病预防控制中心新疆医科大学新疆乌鲁木齐市中医院新疆医科大学第一附属医院肝病专科医院新疆维吾尔自治区疾病预防控制中心 乌鲁木齐830000乌鲁木齐830054乌鲁木齐830000

【摘要】 目的研究输血传播病毒(TTV)在新疆乌鲁木齐市体检高考学生和HBV携带考生中的感染情况,以探讨输血传播病毒的致病特性。方法以公布的TTV第一读码区序列设计两对寡核苷酸引物,用套式PCR方法,对120例体检HB-sAg阴性考生和46例HBV携带考生血清进行TTV-DNA的检测。结果120例体检HBV阴性考生中检出4例TTV-DNA阳性血清,阳性率为3.3%;46例HBV携带考生中检出8例TTV-DNA阳性血清,TTV-DNA阳性率为17.4%,两组相比差异有统计学意义(χ2=7.81,P(0.01)。结论新疆考生中存在TTV的感染,HBV携带考生中TTV的感染率较高。

【Abstract】 ObjectiveTo study the prevalence of transfusion transmitted virus(TTV) in college candidates and HBV carriers in Urumqi.MethodsSera from the examined college candidates with negative HBsAg and HBV carriers were detected by nested polymerase chain reaction(nPCR) assay for the presence of TTV-DNA.ResultsOut of the 166 objects,the rate of TTV was 3.3% in normal college candidates and 17.4% in the positive carriers of hepatitis B virus(HBV).ConclusionsThere is TTV infection in college candidates in Urumqi with high infective rate of TTV in the positive carriers of HBV.

【基金】 国家教育部春晖计划(Z2005-1-65003)
  • 【文献出处】 地方病通报 ,Endemic Diseases Bulletin , 编辑部邮箱 ,2008年02期
  • 【分类号】R193
  • 【下载频次】45
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