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夏连杞贞胶囊治疗胃阴亏损型慢性萎缩性胃炎癌前病变临床研究

Clinical research of Xialianqizhen granule on precancerosis of chronic atrophic gastritis due to gastric-yin deficiency

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【作者】 路文军孙成栋于大猛

【Author】 LU Wen-jun1,SUN Cheng-dong2,YU Da-meng3 (1Wei Chang Hospital of Hebei Province,Weichang 068450,China;2Department of Infection,Beijing Ji Shuitan Hospital,Affiliated to Peking University,Beijing 100035,China;3Wei Chang Traditional Chinese Hospital of Hebei Province,Weichang 068450,China)

【机构】 围场县医院内二科北京积水潭医院感染科围场县中医院内科 河北围场068450北京100035河北围场068450

【摘要】 [目的]观察夏连杞贞胶囊对胃阴亏损型慢性萎缩性胃炎(CAG)癌前病变的逆转作用。[方法]将114例符合标准的CAG胃癌前期病变患者,随机分为夏连杞贞胶囊治疗(治疗)组68例和维酶素对照(对照)组46例进行临床疗效观察。[结果]治疗组总有效率为83.8%,对照组为65.2%,2组差异有统计学意义(P<0.01);治疗组自身前后及与对照组比较,临床症状积分、胃镜像、病理积分、抑杀胃内幽门螺杆菌,差异均有统计学意义(P<0.01,<0.05)。[结论]夏连杞贞胶囊具有较好的临床、病理疗效,是逆转胃阴亏损型胃黏膜癌前病变的有效方药。

【Abstract】 [Objective] To study the reversal effect of Xialianqizhen granule on precancerosis of chronic atrophic gastritis due to gastric-yin deficiency.[Methods]One hundred and fourteen patients with precancerosis of chronic atrophic gastritis due to gastric-yin deficiency were selected and divided at random into Xialianqizhen granule group and control group of Wei meisu.The clinical symptoms and pathological changes were observed.[Results] The effective rate of treatment group was 83.3% vs 65.2% of the control group (P<0.01).Compared with those of pretherapy or control group,clinical symptom integral,gastroscope image,pathology integral and Hp eradication of the treatment group were significantly improved(P<0.01,P<0.05).[Conclusion ]Xialianqizhen granule has better clinical and pathological therapeutic effect and is an effective Chinese prescription.

【基金】 河北省科技攻关计划项目(0627611026)
  • 【文献出处】 中国中西医结合消化杂志 ,Chinese Journal of Integrated Traditional and Western Medicine on Digestion , 编辑部邮箱 ,2007年04期
  • 【分类号】R735.2
  • 【被引频次】26
  • 【下载频次】190
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