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血尿酸、纤维蛋白原、超敏C-反应蛋白与急性脑梗死的关系
Plasma Uric Acid,Fibrinogen,High Sensitive C-reactive Protein and Acute Cerebral Infarction
【摘要】 目的探讨血尿酸(Uric acid,UA)、血纤维蛋白原(Fibrinogen,Fg)、超敏C反应蛋白(high sensitive C-reactive protein,hs-CRP)在急性脑梗死中的意义。方法对脑梗死患者98例及对照组68例进行血UA、Fg、hs-CRP的检测。结果急性脑梗死患者血清UA(334.81±94.54)μmol/L、Fg(3.85±1.18)g/L、hs-CRP(5.08±5.52)mg/L水平明显增高,差异有显著性意义(P<0.05);UA与神经功能缺损程度无关,Fg、hs-CRP与神经功能缺损程度有关。结论Fg、hs-CRP与缺血性脑血管病的发生和神经功能缺损程度有关,UA与缺血性脑血管病的发生有关而与神经功能缺损程度无关。
【Abstract】 Objective To discuss the significance of plasma uric acid(UA),fibrinogen(Fg)and high sensitive C-reactive protein(hs-CRP)in patients with cerebral infarction.Methods The plasma levels of UA,Fg and hs-CRP were measured among cerebral infarction patients(n=98)and control group(n=68).Results In patients with cerebral infarction,the plasma levels of UA,Fg and hs-CRP were(334.81±94.54)μmol/L,(3.85±1.18)g/L and(5.08±5.52)mg/L,respectively,they were significantly higher than the control group(P<0.05);the plasma Fg and hs-CRP were positively related to the neurological deficit degree in cerebral infarction patients,but there was no significant correlation between UA and neurological deficit degree.Conclusion Fg and hs-CRP were related to the formation and progression of cerebral infarction,UA was related to the formation of cerebral infarction but had no effect on the progression.
【Key words】 Uric acid(UA); Fibrinogen(Fg); High sensitive C-reactive protein(hs-CRP); Cerebral infarction(CI);
- 【文献出处】 中国微循环 ,Journal of Chinese Microcirculation , 编辑部邮箱 ,2007年04期
- 【分类号】R743.3
- 【被引频次】20
- 【下载频次】236