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慢性乙肝患者血清自身抗体检测的临床意义

Clinical significant for detection of serum autoantibodies in patients with chronic hepatitis B

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【作者】 周力王长嘉路洪艳陈阳王亮

【Author】 Zhou Li,Wang Chang-jia,Lu Hong-yan,Chen Yang,Wang Liang(Department of Liver Disease,Jilin People′s Hospital,Changchun 130021,China)

【机构】 吉林省人民医院肝病科吉林省人民医院肝病科 长春130021长春130021

【摘要】 目的:评价慢性乙肝与自身免疫的关系。方法:应用荧光标记测定慢性乙肝患者血清中ANA、AMA、SMA抗体。结果:85例慢性乙肝患者血清中自身抗体阳性率约为32.94%,明显高于健康对照组。HBV DNA阳性组与HBV DNA阴性组自身抗体检出率无显著差异性。结论:在慢性乙肝患者常规诊疗中检测自身抗体,对其诊断、鉴别诊断及治疗具有重要价值。

【Abstract】 Objective:To estimate the relationship between chronic hepatitis B and autoimmune.Methods:The fluorescence dye was used to detect the ANA,AMA,SMA in serum of patients with chronic hepatitis B.Results:The positive rate of autoantibodies in chronic hepatitis B was higher in comparison with those in normal group(32.94%,28/85).There were no remarkable differences between autoantibodies positive group and autoantibodies negative group in HBV DNA.Conclusion:Detection of serum autoantibodies in patients with chronic hepatitis B has important value in diagnosis,differential diagnosis and treatment.

【关键词】 慢性乙肝自身抗体
【Key words】 Chronic hepatitis BAutoantibody
  • 【文献出处】 中国卫生检验杂志 ,Chinese Journal of Health Laboratory Technology , 编辑部邮箱 ,2007年09期
  • 【分类号】R512.62
  • 【被引频次】7
  • 【下载频次】94
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