【摘要】 目的评估吸烟和非吸烟老年患者麻醉诱导时的插管反应。方法42例老年男性患者(>65岁),ASAⅠ-Ⅱ级,分为吸烟组(20例)和非吸烟组(22例)。每例患者均使用异丙酚、舒芬太尼和维库溴铵进行麻醉诱导,在插管前,诱导后1、2min和插管后即刻,1、3、5min记录心率、血压。麻醉诱导前测量还原血红蛋白浓度。所有患者由同一个医生进行气管插管。结果心律失常的发生率吸烟组(27.27%)高于非吸烟组(10.00%)。插管即刻吸烟组的心率增幅(41.34%)明显大于非吸烟组(20.88%);吸烟组的收缩压和平均动脉压增幅(45.11%和41.77%)明显大于非吸烟组(23.51%和20.78%)。结论在麻醉诱导插管时老年吸烟患者的心率、血压较老年非吸烟患者的波动明显。且老年吸烟者还原血红蛋白水平明显高于老年非吸烟者,携氧能力相对低下,更容易发生心肌缺血,其麻醉风险高。更多还原

【Abstract】 Objective To compare the induction-intubation response between elder male smokers and non-smokers.Methods Forty two male patients(ASAⅠ～Ⅱ)who underwent general anesthesia were divided into two groups:smokers(n=20)and non-smokers(n=22).Heart rate,blood pressure were measured prior to induction,1,2 minutes after induction and at 1,3,and 5 minutes after intubation.All the patient were intubated by the same doctor.Results Incidence of arrhythymias(27.27%)was higher in smokers compared to non-smokers(10.00%).The percentage of heart rate increase in smokers(41.34%)was much highter than that in non-smokers(20.88%)and percentage of increased blood pressure in smokers(45.11% and 41.77% for systolic and mean pressure respectively)was higher than that in non-smokers(23.51% and 20.78%).Conclusion During induction-intubation period,heart rate?blood pressure showed more pronounced fluctuations in smokers than in non-smokers(P < 0.05).更多还原