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低浓度槟榔碱杀螺作用的实验观察
Study on killing-oncomelania snail with low-concentration arecoline
【摘要】 采用WHO推荐的"杀螺剂实验室终筛法"中的浸泡法,将受试钉螺分为6组,分别投入浓度为0.5、1.0、1.5、2.0 mg/L的槟榔碱溶液中,对照组溶液分别为2.0 mg/L的氯硝柳胺以及去氯自来水。经上述浓度槟榔碱作用1 h,钉螺的开厣率依次为55.6%、90.0%、92.2%、95.6%,附壁率均为0,氯硝柳胺对照组开厣率为13.3%,附壁率为1.1%,去氯水组开厣率及附壁率均为77.8%;槟榔碱作用24 h钉螺死亡率依次为91.2%、95.6%、84.4%、73.3%,氯硝柳胺对照组为100%,去氯水组为0。24 h内不同浓度槟榔碱组钉螺头足部软体均肿胀明显,对照组无肿胀。表明槟榔碱在极低浓度时即具有显著的杀灭钉螺作用,且能够抑止钉螺上爬附壁。
【Abstract】 Using the methods of "Final screening method in the lab of oncomelania snail-killing drugs" issued by WHO.The oncomelania snails were divided into 6 groups and putted into 0.5 mg/L,1.0 mg/L,1.5 mg/L and 2.0 mg/L arecoline solutions,water got rid of chlorine and 2.0 mg/L of Niclosamide respectively.After the arecoline aforementioned solution reaction,the rates of the oncomelania snail extending operculum were about 55.6%,90.0%,92.2%,95.6% respectively,and all the climbing up rates were 0.The rates of extending operculum and the rates of climbing adhesion of the control group of Niclosamide were 13.3%and 1.1%,furthermore.The rate of extending operculum and the rate of climbing adhesion of control group of water getted rid of chlorine were 77.8%.The rates of death of oncomelania snail for 24 hours turned out were about 92.2%,95.6%,84.4%,73.3% in the arecoline solutions and the control group of Water got rid of chlorine was 0,and control group of 2.0 mg/L of Niclosamide was 100%.The swelling of oncomelenia foot software were obvious in different density arecoline group in 24 hours.But the control groups almost all occured the negative.The results show that the arecoline with ultra low concentration has the notable effect in killing the oncomelenia snail and inhibiting the climbing up of oncomelenia snail.
- 【文献出处】 中国病原生物学杂志 ,Journal of Pathogen Biology , 编辑部邮箱 ,2007年06期
- 【分类号】R184
- 【被引频次】13
- 【下载频次】103