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碘干预对燃煤氟中毒地区儿童甲状腺影响的研究

Effects of Iodine Intervention on Thyroid Gland of Children in Coal-burning Fluorosis Area

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【作者】 李晓松; 姚仲英; 邹亚丁; 陈世清; 陈剑;

【Author】 LI Xiao-song,YAO Zhong-ying,ZOU Ya-ding,et al.Institute for Endemic Disease Control,Guizhou Disease Prevention and Control,Guiyang 550004,China

【机构】 贵州省疾病预防控制中心地方病防治研究所; 贵州省疾病预防控制中心地方病防治研究所 贵阳550004; 贵阳550004;

【摘要】 目的了解食盐加碘以来贵州燃煤氟中毒病区儿童碘缺乏病情指标的变化。方法采用现场流行病学抽样调查方法,对贵州氟中毒重病区织金县八步乡儿童进行尿碘水平及甲状腺肿大率调查,并与历史本底资料对比。结果被调查的氟病区儿童尿碘中位数为338.7μg/L,高于补碘前3倍,66.70%的儿童尿碘水平高于300μg/L,超过WHO推荐的100~200μg的日摄入量;7~14岁儿童青少年甲状腺肿大率7.1%,是补碘前(0.3%)的23.7倍。结论贵州有37个燃煤型氟中毒病区县,病区人口1900余万,历史上是碘缺乏病的轻病区,八步乡儿童青少年甲状腺肿大率上升的原因有待进一步研究。

【Abstract】 Objective To know children’s current state of iodine deficiency disorders(IDD) after universal salt iodization in coal-burning fluorosis area. Method Field epidemiological investigation was used.Students aged 7~14 were selected and the level of urinary iodine and rate of goiter were determined and compared with history data. Results The median of urinary iodine was 338.7 μg/L,which was three times to that of 1983;the urinary iodine level in 66.7 percent of cases exceed 300 μg/L,which was higher than 100~200 μg recommended by WHO.The goiter rate was 23.7 times to that of 1983. Conclusion There are 37 coal-burning fluorosis counties with 1 900 population in Guizhou which are low-IDD area in history.Reasons of the rising of children’s goiter rate should be further studied.

【关键词】 碘干预; 燃煤型氟中毒; 儿童; 甲状腺肿;
【Key words】 Iodine intervention; Fluorosisd; Children; Goiter;
  • 【文献出处】 中国预防医学杂志 ,China Preventive Medicine , 编辑部邮箱 ,2007年03期
  • 【分类号】R725.9
  • 【被引频次】6
  • 【下载频次】52
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