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蒙古黄芪地上部分的黄酮类成分

Flavonoids From the Aerial Parts of Astragalus mongholicus

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【作者】 毕志明余庆涛李萍林云高晓丹

【Author】 BI Zhi-Ming, YU Qing-Tao, LI Ping, LIN Yun, GAO Xiao-Dan Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Ministry of Education, Nanjing 210038, China

【机构】 中国药科大学现代中药教育部重点实验室中国药科大学现代中药教育部重点实验室 南京210038南京210038

【摘要】 目的:研究蒙古黄芪地上部分的黄酮类化学成分。方法:运用各种柱层析技术进行分离纯化,理化性质和光谱分析法鉴定化学成分。结果:分离并鉴定了6个黄酮类化合物,分别为山柰素-4′-甲醚-3-β-D-葡萄糖苷(Ⅰ),异鼠李素-3-β-D-葡萄糖苷(Ⅱ),异槲皮苷(Ⅲ),沙苑子苷(Ⅳ),odoratin(Ⅴ),odoratin-7-O-β-D-葡萄糖苷(Ⅵ),以及1个皂苷类化合物alexandrosideⅠ(Ⅶ)。结论:化合物Ⅴ为首次从该属植物中分得,化合物Ⅳ、Ⅵ、Ⅶ为首次从该植物中分得。

【Abstract】 AIM: To study flavonoids from the aerial parts of Astragalus mongholicus. METHODS: The chemical constituents were isolated and purified with various column chromatography and the structures were identified by spectal analyses. RESULTS: Six flavonoids and one triterpene saponin were isolated and their structures were identified as kaempferol-4′-methylether-3-β-D-glucoside(Ⅰ), isorhamnetin -3-β-D-glucoside(Ⅱ),isoquercitrin(Ⅲ), complanaruside(Ⅳ),odoratin(Ⅴ), odoratin-7-O-β-D-glucoside(Ⅵ) and alexandroside Ⅰ(Ⅶ). CONCLUSION:Compound Ⅴ were isolated from Genus Astragalus for the first time and compounds Ⅳ、Ⅵ、Ⅶ were firstly isolated from this plant.

【关键词】 蒙古黄芪地上部分黄酮类成分
【Key words】 Astragalus mongholicusAerial partsFlavonoids
【基金】 国家自然科学基金资助项目(No30472160)
  • 【文献出处】 中国天然药物 ,Chinese Journal of Natural Medicines , 编辑部邮箱 ,2007年04期
  • 【分类号】R284.1
  • 【被引频次】59
  • 【下载频次】899
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