【摘要】 目的研究岩黄连(CorydalissaxicolaBunting)的化学成分。方法采用、硅胶低压柱层析、制备性薄层层析和重结晶等方法进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果从岩黄连中分离得到14个化合物,分别为去氢岩黄连碱(dehydrocavidine,1)、黄连碱(coptisine,2)、齐墩果酸(oleanolicacid,3)、刺檗碱(oxyacanthine,4)、胡萝卜苷(daucosterol,5)、别隐品碱(allocryptopine,6)、β-谷甾醇(β-sitosterol,7)、白桦脂醇(betulin,8)、环桉烯醇(cycloeucalenol,9)、白桦脂酸(betulinicacid,10)、β-香树脂醇乙酸酯(β-amyrinacetate,11)、小檗碱(berberine,12)、四氢掌叶防己碱(tetrahydropalmatine,13)、巴马汀(palmatine,14)。结论化合物3~11、14为首次从该植物中分离得到。更多还原

【Abstract】 AIM: To study the chemical constituents from Corydalis saxicola Bunting. METHOD: Isolation and purification were carried out by silica gel column chromatography and recrystallization etc. Structural determination of the pure compounds was based on physico-chemical properties and various spectral data analysis ( 1 H?NMR , 13 C?NMR , IR, ESI-MS). RESULT: Fourteen compounds were obtained from Corydalis saxicola, identified as dehydrocavidine (1), coptisine (2), oleanolic acid (3), oxyacanthine (4), daucosterol (5), allocryptopine (6), β-sitosterol (7), betulin (8), cycloeucalenol (9), betulinic acid (10), β-amyrin acetate (11), berberine (12), tetrahydropalmatine (13) and palmatine (14). CONCLUSION: Compounds 3～11、14 were isolated from this plant for the first time.更多还原