【摘要】 目的探讨腹腔镜手术治疗药物不敏感多囊卵巢综合征(PCOS)的临床应用价值。方法对42例PCOS患者采用腹腔镜下卵巢打孔术和卵巢楔形切除术,观察术后月经、排卵及妊娠情况,比较手术前后相关激素水平变化。结果腹腔镜术后月经恢复正常者占62.16%,排卵率88.15%,妊娠率67.57%;术后血黄体生成素(LH)和雄激素(T)水平明显降低,血卵泡生成素(FSH)轻度升高,空腹血胰岛素(FINS)和胰岛素样生长因子-1(IGF-1)无明显变化。结论腹腔镜手术是治疗药物不敏感PCOS的优选方法,可提高患者的排卵率、妊娠率和对药物的敏感性。更多还原

【Abstract】 [Objective] To study the clinical value of laparoscopic treatment of polycystic ovarian syndrome(PCOS)with drug tolerance.[Methods] Laparoscopic drilling and wedge resection of ovary were used to treat 42 cases of PCOS.The menstruation,ovulation and pregnancy were observed,and related hormones were compared between preoperation and postoperation.[Results] The percentage of menstruation reversion was 62.16%,ovulation rate was 88.15% and pregnancy rate was 67.57% after laparoscopic operation.Dramatical decreases were observed in the postoperative levels of blood lutuneizing hormone(LH)and androgen(T),a mild increase in blood follicle-stimulating hormone(FSH),but there were no significant differences in the levels of fasting insulin(FINS)and insulin-like growth factor-1(IGF-1)between laparoscopic preoperation and postoperation.[Conclusions] Laparoscopic operation is a suitable treatment for PCOS with drug tolerance,which could increase the ovulation rate,pregnancy rate and sensitivity to ovulation drug.更多还原