【摘要】 目的:探讨环境因素和遗传因素对儿童血压的影响。方法:通过双生分析法和群体调查对血压的影响因素进行对比分析。结果:双生儿分析法和群体调查其血压频数分布呈正偏态分布和出现双峰的现象;异卵双生儿的血压相关系数大于同卵双生;异卵双生儿与父母血压的相关系数大于同卵双生与父母血压的相关系数;双生儿SBP与DBP之间相关系数大于非双生儿相关系数;家庭聚集性明显,父母与父母之间血压相关系数有非常显著意义;同卵双生儿与异卵双生儿血压偏高率分别为7.5%和7.0%,两者差异无统计学意义;母亲有高血压史,其子女有高血压者是母亲无高血压者的2.3倍,两者差异有统计学意义。结论:儿童血压频数分布双生儿呈正偏态分布,一般群体出现双峰。前者与年龄组分布不均有关,后者提示可能存在二个相异“质”的不同群体。血压的变异是遗传和环境共同作用的结果;儿童血压随年龄变化是生长发育的一种伴随现象;低出生体重可使生后血压升高。更多还原

【Abstract】 Objective:To study on the effects of environment and heredity on children’s blood pressure through twinborn analytical method and group investigation.Methods:Blood pressure was measured according to dometic unified methods.Fetal membranes were inquired to identify egg.Results:The frequency of blood pressure presented a normal distribution and twin peak sign through the twinborn analytical method and group investigation.The blood pressure correlation coefficient of the dizygotic twins was larger than that of the identical twins;the blood pressure correlation coefficient of the dizygotic twins’ parents was larger than that of the identical twins’ parents;the correlation coefficient of the twinborn children between SBP and DBP was larger than that of the non-twinborn children.The family aggregation was obvious;the blood pressure correlation coefficient between the parents had obvious significance.The identical illness rate of the identical twins and the dizygotic twins was 7.5%and 7.0% respectively.The difference between the two had no significance statically.The chidren whose mothers had case history of high blood pressure would suffer from the high blood pressure 2.3 times of those whose mothers hadn’t the case history.The rate had significance statistically.Conclusion:The blood pressure frequency of the twinborn children presents nomad distribution while the frequency of the general groups shows the twin peak sign.The former has some relation with uneven age distribution.The later points out the possibility of the two different groups with the two different "qualities".The blood pressure variation is the results of the interaction of the heredity and environment.The change of the children blood pressure with their growth is a collateral phenomenon.The children born with low weight may cause their blood pressure to rise after their birth.更多还原