【摘要】 目的探讨子宫体原发性弥漫性B细胞淋巴瘤的病理诊断与鉴别诊断要点。方法对2例子宫体原发性弥漫性B细胞淋巴瘤进行临床病理特点观察,使用LCA、CD30、CD79a、CD68、CD45RO、CD3、CD20和CEA等免疫组化染色辅助诊断,并文献复习。结果子宫体原发性弥漫性B细胞淋巴瘤临床诊断困难,镜下病理形态多样,可见子宫内膜和/或肌层内淋巴样细胞增生,免疫组化B细胞标记(+)。结论子宫原发性弥漫性B细胞淋巴瘤少见,临床易漏诊且侵袭性较高,因此准确、完整的病理诊断对预后治疗十分重要,免疫组化有辅助诊断作用。更多还原

【Abstract】 Objective To study the pathologic diagnosis and differential diagnosis of primary diffuse large B-cell lymphoma of uterine body.Methods 2 cases of primary diffuse large B-cell lymphoma of uterine body were reported.Immunohistochemical stains for LCA,CD30,CD79a,CD68,CD45RO,CD3,CD20 and CEA were performed and also related literatures reviewed.Results The clinical diagnosis of primary diffuse large B-cell lymphoma of uterine body was difficult.The pathological feature was various.There was proliferation of lymphoid cells in endometrium and muscular layers of womb.Large B cells were identified with immunohistochemical staining.Conclusion The primary diffuse large B-cell lymphoma of uterine body is rare with high invasive capacity and easily mis-diagnosed.Accurate and complete diagnosis is very important for this tumor because the treatment and prognosis are different for different histological types.Immunohistochemistry is useful for pathologic diagnosis of this tumor.更多还原