【摘要】 目的:用HPLC法建立复方肾通颗粒的指纹图谱。方法:用Alletch C18(4.6 mm×250 mm,5μm)色谱柱,乙腈-水为流动相,线性梯度洗脱,检测波长:270 nm,流速:1.0 mL/min。结果:制剂中选定的共有峰分离良好,且重现性RSD为1.8%。结论:该方法为肾通颗粒的质量控制提供了较全面的信息。更多还原

【Abstract】 AIM: To establish a RP-HPLC method to determine the fingerprint of Shentong granules. METHODS: Chromatographic conditions consisted of Alltech ODS column and the mobile phase composed of a mixture of acetonitrile-water(gradient elution),detection wavelength at 270 nm.The flow rate was 1.0 mL/min. RESULTS: A HPLC fingerprint determination with a good reproducibility was established,which could separate main principles of Shentong granules. CONCLUSION: The method can provide more information for the quality control of Shentong granules.更多还原