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痛风的发病机制
Pathogenesis of Gout
【摘要】 痛风由尿酸盐结晶沉积诱发关节炎性反应,常伴有高尿酸血症,尿酸的产生增多和排泄减少导致高尿酸血症,而尿酸盐结晶通过炎性介质诱发炎性反应,了解高尿酸血症的原因和炎性反应的作用机制对痛风的治疗有重要意义。
【Abstract】 Gout is a type of inflammatory arthritis resulting from deposit of urate crystal,which is often companyed by hyperuricacidemia induced by icreased production and decreased excretion of uric acid.Urate crystal can induce inflammatory reaction by inflammatory mediators.It has great significance.to know the etiology of gout and its mechanism of inflammatory reaction for the therapy of gout.
- 【文献出处】 医学综述 ,Medical Recapitulate , 编辑部邮箱 ,2007年21期
- 【分类号】R589.7
- 【被引频次】83
- 【下载频次】2399