【摘要】 [目的]了解2002~2004年大汶河主干流域研究区及对照区居民的死亡状况及主要恶性肿瘤的疾病负担。[方法]对大汶河主干流域研究区及对照区进行恶性肿瘤为主的死因回顾性调查,按“ICD-10”对死因资料整理分类,应用YPLL、AYPLL、WYPLL和VYPLL等指标进行分析。[结果]2002~2004年大汶河主干流域肿瘤YPLL率达14.82‰,AYPLL为8.29人年,平均WYPLL为5.89人年,平均VYPLL为1.33人年,居全死因YPLL位次第1位,其SYPLL率显著高于对照区(χ2=156.48,P<0.01);肝癌列主要恶性肿瘤YPLL率第1位;男、女性YPLL位次有所不同,男性SYPLL率普遍高于女性;大汶河主干流域研究区上游SYPLL率显著低于中下游(χ2=948.08,P<0.01)。[结论]肿瘤是大汶河主干流域研究区影响当地居民健康和寿命的最大危害,尤以肝癌为甚;中下游是重点地区,应在该地区开展长期的肿瘤监测和防治研究,努力降低肿瘤的危害。更多还原

【Abstract】 [Objective]To explore the current mortal status and the burden of disease of main malignant tumors among residents in the main trunk-stream areas of Dawen river and its control areas in Shandong province from 2002 to 2004.[Methods]With the cross-sectional study method,a retrospective investigation for all death causes mainly comprised malignant tumor was carried out among residents in the main trunk-stream areas of Dawen river and its control areas.The data were deal and classified by ICD-10,and were analyzed with the statistic indexes such as YPLL,AYPLL,WYPLL and VYPLL,etc.[Results]The YPLL rate of malignant tumors in the main trunk-stream areas of Dawen river from 2002 to 2004 was 14.82 per 1 000,the AYPLL was 8.29 per year,the mean WYPLL was 5.89 per year,the mean VYPLL was 1.33 per year,the YPLL was firstly ranked among all death causes,and the SYPLL rate was significantly higher than that in control areas(χ2=156.48,P<0.01).The SYPLL rate of Liver cancer was the first rank in main malignant tumors.The rank of YPLL of male was different with female,and the SYPLL rate of male was generally higher than female.The SYPLL rate among residents in the upriver areas was significantly lower than that in the mid-river and downriver areas(χ2=948.08,P<0.01).[Conclusion]Malignant tumors have severely damaged the health and life of local residents in the main trunkstream areas of Dawen river,of which liver cancer is especially representative. The mid-river and downriver areas of Dawen river is the emphasis,and long-term researches and survey should be carried out to take appropriate measures for the malignant tumors and make great efforts to reduce the harm.更多还原