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Cell Toxicity Effect of Cadmium on Yeast Cells by Detecting NADH Autofluorescence

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【Author】 LIANG Ju1, CAI Ruxiu2, WU Wenlan3, LIU Zhihong2, 1. College of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology, Luoyang 471003, Henan, China; 2. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei, China ; 3. College of Life Sciences, Wuhan University, Wuhan 430072, Hubei, China

【摘要】 The cytotoxic effect of cadmium is studied by detecting intracellular nicotinamide adenine dinucleotidea(NADH) autofluorescence in this work. NADH autofluorescence in processes of cadmium-induced apoptosis, necrosis and reversible injury are recorded timely. The relativity between time course of NADH autofluorescence and cadmium toxicity is established. The cell toxicity effect of Cadmium on yeast cells is studied by detecting the time courses of intracellular reduced NADH autofluorescence in this work. The relativity between time courses of NADH autofluorescence and Cadmium toxicity is established.

【Abstract】 The cytotoxic effect of cadmium is studied by detecting intracellular nicotinamide adenine dinucleotidea(NADH) autofluorescence in this work. NADH autofluorescence in processes of cadmium-induced apoptosis, necrosis and reversible injury are recorded timely. The relativity between time course of NADH autofluorescence and cadmium toxicity is established. The cell toxicity effect of Cadmium on yeast cells is studied by detecting the time courses of intracellular reduced NADH autofluorescence in this work. The relativity between time courses of NADH autofluorescence and Cadmium toxicity is established.

【关键词】 Cadmium； reduced nicotinamide adenine dinucleotidea (NADH)； cell toxicity； yeast cells；
【Key words】 Cadmium； reduced nicotinamide adenine dinucleotidea (NADH)； cell toxicity； yeast cells；
【基金】 Supported by the National Natural Science Foundation of China (20275027)
  • 【文献出处】 Wuhan University Journal of Natural Sciences ,武汉大学自然科学学报(英文版) , 编辑部邮箱 ,2007年02期
  • 【分类号】X172
  • 【下载频次】46
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