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陕、甘两省酒精性与非酒精性脂肪肝流行病学分析

Epidemiological analysis of alcoholic and non-alcoholic fatty liver in Shanxi and Gansu province

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【作者】 延华鲁晓岚罗金燕周小彦

【Author】 YAN Hua,LU Xiaolan,LUO Jinyan,ZHOU Xiaoyan Department of Digestive Disease,the Second Affiliated Hospital,School of Medicine of Xi′an Jiaotong University,Xi′an,710004,China

【机构】 西安交通大学医学院第二附属医院消化内科西安交通大学医学院统计学教研室 陕西西安710004陕西西安710004

【摘要】 目的调查陕西省和甘肃省成人酒精性、非酒精性脂肪肝患病率并分析相关危险因素。方法采用横断面调查的方式,调查两省成人脂肪肝患病率,内容包括填写问卷,测量身高、体重、腰围,生化检查和B超检查。结果共调查1500人,其中男性1023名,女性477名。共检出脂肪肝247例,其中饮酒率、酒精性脂肪肝、非酒精性脂肪肝的检出率分别为56.53%、3.87%、12.60%。男性脂肪肝患病率无论是酒精性还是非酒精性均高于女性(P<0.05)。脂肪肝的患病率随年龄的增加而上升。经Logistic多元回归分析,年龄、日酒精摄入量、饮酒年限、BMI与酒精性脂肪肝密切相关,其中以日酒精摄入量相对风险度最高(OR=9.941,95%CI4.803~20.577);年龄、男性、高脂血症、BMI、腰围与非酒精性脂肪肝密切相关,其中以高脂血症相对风险度最高(OR=3.750,95%CI2.752~6.745)。结论两省成人脂肪肝患病率较高,以非酒精性脂肪肝为主。肥胖、饮酒是脂肪肝最重要的危险因素。

【Abstract】 Objectives To evaluate the prevalence of alcoholic and non-alcoholic fatty liver among adult residents in Shanxi and Gansu province and to determine related risk factors.Methods By cross-sectional study in the two provinces including questionaire,height,body weight,waist circumference,biochemical tests and ultrasonographic exzamination of liver.Results A total of 1 500 persons took part in this survey.Of which 1023 were males and 477 were females.Fatty liver were detected in 247 persons.The prevalence of alcohol addict,alcoholic fatty liver and non-alcoholic fatty liver were 56.53%,3.82%,12.60%, respectively.The prevalence of fatty liver in males was significantly higher than that in females(P<0.05).It was increased with the age. Multiple Logistic regression analysis demonsstrated that alcoholic fatty liver was closely related to age,hyperlipoidemia,daily alcohol intake,and BMI,of which the daily alcohol intake was the highest risk factors(OR=9.941,95%C14.803~20.577). Non-alcoholic fatty liver was correlated to age,male,hyperlipoidemia,BMI and waist circumference,of which hyperlipoidemia was the highest risk factors(OR=3.750, 95%C12.752~6.745).Conclusions Fatty liver is prevalent among adult residents in the two provinces.Non-alcoholic fatty liver is the major type.Obesity and drinking are the major risk factors of fatty liver.

【关键词】 脂肪肝患病率危险因素流行病学
【Key words】 Fatty liverPrevalenceRisk factorsEpidemiology
  • 【文献出处】 胃肠病学和肝病学杂志 ,Chinese Journal of Gastroenterology and Hepatology , 编辑部邮箱 ,2007年04期
  • 【分类号】R575.5
  • 【被引频次】49
  • 【下载频次】477
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