【摘要】 目的评价急性ST段抬高心肌梗死(STEMI)患者急诊冠状动脉介入治疗(PCI)中应用DiverCE血栓抽吸装置的效果与安全性。方法选择抚顺市中心医院2006年7月至2007年6月接受直接PCI的STEMI患者46例,分成血栓抽吸组与直接PCI组,比较两组间2h胸痛缓解率、ST段回落率、TIMI3级血流、肌酸磷酸激酶(CK)及其同功酶(CK-MB)峰值、左室射血分数(LVEF)及术后1个月内心脏不良事件发生率。结果血栓抽吸组的2h胸痛缓解率、ST段回落率、TIMI3级血流、CK及CK-MB峰值、LVEF值明显优于直接PCI组(P<0.05),术后1个月内心脏不良事件发生率两组差异无显著性意义(P>0.05)。结论PCI中应用DiverCE血栓抽吸装置能明显减少冠状动脉血栓及远端栓塞,有效地改善心肌灌注。更多还原

【Abstract】 Objective To assess the effect and safety of applying Diver CE thrombus-aspirating device during direct percutaneous coronary intervention(PCI)in pations with ST-segment elevation myocardial infarction(STEMI). Methods Select 46 patients with STEMI who underwent direct PCI between July,2006 and June,2007 in Fushun Central Hospital. Dividing these patients into thrombus-aspirating group and direct PCI group,comparing the difference in chest pain relieving.magnitude of ST-segment declining in 2h,TIMI flow grade 3,the maximum value of CK and CK-MB,EF and MACE outcome(death、myocardial infarction and targert vessel revascularization).Results The percent of chest pain relieving、magnitude of ST-segment declining 、TIMI flow grade 3、the maximum value of CK and CK-MB,and EF in thrombus-aspirating group are piror to the direct PCI group(P<0.05). MACE outcome in one month is no statistical significance(P>0.05).Conclusion applying Diver CE thrombus-aspirating device during PCI can obviously reduce thrombus in coronaty artery and distal embolization,improve myocardial reperfusion more effectively.更多还原