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葛仙米藻蓝蛋白抗氧化作用研究

Study on Antioxidation Activities of Phycocyanin from Nostoc sphaeroids Kutz

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【作者】 汪兴平谢笔均潘思轶陈德文赵利霞

【Author】 WANG Xing-ping1,XIE Bi-jun2,PAN Si-yi2,CHEN De-wen2,ZHAO Li-xia2 (1.Hubei Key Laboratory of Biological Resource Conservation and Utilization, School of Biological Science and Technology, Hubei Institute for Nationalities, Enshi 445000, China; 2.College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070,China)

【机构】 湖北民族学院生物科学与技术学院湖北省生物资源保护与利用重点实验室华中农业大学食品科技学院华中农业大学食品科技学院 湖北恩施445000湖北武汉430070

【摘要】 通过非脂质体系抗氧化实验、体外抗氧化实验研究了葛仙米藻蓝蛋白的抗氧化能力。结果表明:葛仙米藻蓝蛋白对清除O2·、·OH自由基和H2O2具有较好的量效关系。在体外反应体系中,葛仙米藻蓝蛋白能显著地降低MDA生成和血和肝中过氧化物的含量,起到保护细胞膜和红血球的作用。显示葛仙米藻蓝蛋白对小鼠肝线粒体损伤具有保护作用,并能显著影响血浆的抗活性氧能力。

【Abstract】 In this experiment, ability of anti-oxidation of phycocyanin in Nostoc sphaeroids Kutz by anti-oxidation experiment with non-lipid system and anti-oxidation in vitro was studied. The results indicated that relationship between concentration and scavenging effect of phycocyanin on superoxide free radical (O·2), hydroxyl free radical (·OH) and peroxide hydrogen (H2O2) was evident. Contents of MDA and peroxide in blood and liver of mice were reduced in vitro, so phycocyanin could cell protect membrane and erythrocyte. Obviously, phycocyanin in Nostoc sphaeroids Kutz could protect rat liver plastomasme from being damnified and effected evidently on ability of anti-oxygen of blood plasma.

【基金】 湖北省自然科学基金项目(2003ABA068);湖北省科技攻关项目(2002A201C15);湖北省优秀中青年科技创新团队计划项目(鄂科教[2005]3)
  • 【文献出处】 食品科学 ,Food Science , 编辑部邮箱 ,2007年12期
  • 【分类号】R151
  • 【被引频次】40
  • 【下载频次】672
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