【摘要】 【目的】探讨滋阴清肝法治疗成年女性阴虚肝热型痤疮的疗效。【方法】采用随机数字表法将患者随机分为治疗组和对照组,两组在给予痤灵酊(主要成分有丹参、白芷、北芪等)外搽治疗的基础上,治疗组给予滋阴清肝消痤方(女贞子、旱莲草、柴胡、丹参等)口服治疗,对照组给予美满霉素口服治疗,1个疗程(28 d)后比较两组疗效。【结果】治疗组治愈4例,显效14例,有效26例,无效8例,总有效率为84.6%;对照组治愈5例,显效13例,有效25例,无效5例,总有效率为89.6%;经统计学处理,两组疗效相仿(P>0.05)。但治疗组发生药物不良反应事件7例,对照组发生不良反应事件9例,治疗组较对照组少。【结论】滋阴清肝消痤方治疗成年女性阴虚肝热型痤疮疗效好,与美满霉素的疗效相当,而且发生不良事件少,症状轻。更多还原

【Abstract】 【Objective】To investigate the method of nourishing yin and clearing liver for adult female acne vulgaris(AV) with Yin deficiency and liver heat.【Methods】One hundred and twenty adult female AV patients were randomized into two groups by random number table.The two groups received external application of Cuo Ling Tincture(CLT,mainly composed of Radix Salviae Miltiorrhizae,Radix Angelicae Dahuricae,Radix Astragali,etc.),and group A was treated with Ziyin Qinggan Xiaocuo Prescription(ZQXP,mainly composed of Fructus Ligustri Lucidi,Herba Ecliptae,Radix Bupleuri,Radix Salviae Miltiorrhizae,etc.)and group B with minocyclin additionally.The treatment lasted 28 days.After treatment,the therapeutic effect were compared between the two groups.【Results】In group A,4 were cured,14 markedly effective,26 effective and 8 ineffective,the total effective rate being 84.6%.In group B,5 were cured,13 markedly effective,25 effective and 5 ineffective,the total effective rate being 89.6%,which is similar to that in group A(P>0.05).Adverse action was found in 7 patients of group A and in 9 of group B.【Conclusion】ZQXP has a good therapeutic effect for adult female AV,which is similar to minocyclin.Meanwhile,ZQXP has less and slight adverse actions.更多还原