【摘要】 目的开展预防接种副反应试点监测,探寻预防接种副反应监测的有效方法。方法建立全省预防接种副反应监测报告网,通过中国免疫规划监测信息管理系统逐级报告预防接种副反应,并做好监测结果的评估与分析。结果全省22个县市报告预防接种副反应,报告接种副反应57例。分类属疫苗反应37例(64．91%),偶合症10例(17．54%),原因不明或待定9例(15．78%),实施差错1例(1．75%)。临床诊断为过敏反应18例(31．58%),发热18例(31．58%),病因不明9例(15．79%),上呼吸道感染4例(7．02%),卡介苗接种加重反应3例(5．26%),病毒性脑炎3例(5．26%),瘢痕反应和接种部位错误各1例(3．51%)。年龄＜1岁21人(36．84%),1～5岁29人(50．88%),10～20岁5人(8．77%),30～50岁1人(1．75%),不详1人(1．75%)。接种与反应间隔时间,在0～3d 50例(87．7%),15d以上7例(12．3%)。结论开展预防接种副反应监测是免疫规划工作的重要内容之一,本次监测试点方案可操作性强,监测系统进一步完善后可考虑全面推行。更多还原

【Abstract】 Objective To monitor adverse reactions due to vaccination.Methods The monitoring - and - vaccination-asso- ciated adverse-reaction-reporting network was established in whole Hubei Province and the vaccination - associated adverse reac- tions were monitored and reported from lower level to higher level through China expanded immunization program monitoring informa- tion system.Results Vaccination-associated adverse reactions were reported in 22 counties and cities and 57 cases were report- ed,including 37 cases due to vaccination(64.91%),10 coincident cases (17.54%),9 unknown causes (15.78%),1 mistaken case(1.75%).Based on clinical diagnosis,18 were diagnosed as allergic reaction (31.58),18 were diagnosed as fever(31. 58%),9 were unidentified 15.78%),4 were diagnosed as upper respiratory tract infection (7.02%),3 were diagnosed as BCG re- action(5.26%),3 were diagnosed as viral encephalitis(5.26%) and the other 2 were scar reaction and wrong vaccination site (3. 51%).About 87.72% of adverse reactions occurred in the age groups of 1-5 years old and 87.7% of the adverse reactions were observed from 0 to 3 days after vaccination.Conclusion The work of monitoring vaccination associated adverse reactions is one of the important task of EPI and be carried out after pilot trial.更多还原