【摘要】 目的:考察生力胶囊对正常大鼠、去势大鼠性活动能力的影响。方法:将生力胶囊按0.35、0.70、1.40 g/kg给雄性大鼠灌胃,观察并记录捕捉潜伏期、捕捉次数、射精潜伏期、射精次数,评价生力胶囊对正常大鼠交配能力的影响;利用去势动物模型,测定勃起潜伏期、包皮腺、精囊腺、前列腺脏器系数,观察生力胶囊对去势雄性大鼠性器官的生长发育及性功能的影响。结果:生力胶囊各剂量组(0.35、0.70、1.40 g/kg)对大鼠交配潜伏期有缩短作用(P<0.01),0.35、1.40g/kg剂量组对捕捉次数有显著增加作用(P<0.05),0.35 g/kg剂量组对勃起潜伏期有缩短趋势,0.70 g/kg剂量组对精囊腺和前列腺的萎缩有较强的对抗趋势。结论:生力胶囊能够显著提高雄性大鼠的性活动能力,提示生力胶囊在增强性欲,增加勃起次数,增强性活动能力等方面表现出较强的作用,其作用机理有待于进一步研究。更多还原

【Abstract】 Objetive: To evaluate the effects of Shengli capsules on the sexual ability of normal and castrated male rats. Methods: Shengli capsules were given by intragastric administration to 100 experimental male rats at different doses of 0.35,0.70 and 1.40 g / kg.Data were collected and analyzed,including capture latency period,times of capture,sexual endurance and times of ejaculation,to assess the effects of Shengli capsules on the sexual ability of the rats.The Castrated Animal Impotence Model was employed to determine the erectile latency period and the function parameters of the preputial gland,seminal vesicle and prostate,so as to test the effects of Shengli on the development of the rats’ sexual organs. Results: Shengli was proved to be effective in shortening copulation latency in the dose groups of 0.35,0.70 and 1.40 g / kg(P<0.01),increasing significantly the frequency of capture in the high-and low-dose groups of 0.35 and 1.40 g / kg(P<0.05),reducing the latency period to erection in the low-dose group of 0.35 g / kg,and blocking the shrink of the seminal vesicle and prostate in the medium-dose group of 0.70 g / kg. Conclusion: Shengli is significantly effective in enhancing the sexual ability of male rats: it can boost libido,increase erection frequency and improve sexual performance.However,further studies have yet to be done on its action mechanisms.更多还原