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供精自愿人群生物学特征与精液指标的相关性分析

Correlation Between Biological Characteristics of Volunteer Donors and Sperm Parameters

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【作者】 王奇玲唐立新马春杰文任乾刘美意邓顺美庄嘉明

【Author】 WANG Qi-ling,TANG Li-xin,MA Chun-jie,WEN Ren-qian,LIU Mei-yi,DENG Shun-mei,ZHUANG Jia-ming Human Sperm Bank,Guangdong Family Planning Hospital,Guangzhou,Guangdong 516000,China

【机构】 广东省计划生育专科医院人类精子库广东省计划生育专科医院人类精子库 广东广州510600广东广州510600

【摘要】 目的:探讨供精自愿人群的生物学特征与精液指标的关系。方法:778例初次捐献精液的供精自愿者的精液用WHO推荐的标准化方法在计算机辅助精子分析系统上检测精子密度、活动率、曲线速度(VCL)、直线速度(VSL)、平均路径速度(VAP)、精子头侧摆幅度(ALH)、直线性(LIN)、前向性(STR)、鞭打频率(BCF)等精液指标,并登记相应的生物学特征。结果:供精自愿者中在校学生的比例超过1/3,89.2%年龄35岁以下,71.6%身高为166~175 cm,91.7%属于正常体重,77.1%具有专科及以上文化程度;精子密度的中位数为107.00×106/m l,活动率的中位数为75%;生物学特征与精液指标的综合分析显示与年龄有较弱的相关关系的指标包括:精子密度(r=0.210,P=0.000)、活动率(r=0.213,P=0.000)、容积(r=0.165,P=0.002)、VAP(r=0.259,P=0.000)、VSL(r=0.281,P=0.000)、VCL(r=0.190,P=0.000)、BCF(r=-0.243,P=0.000)、LIN(r=0.192,P=0.000),26~35岁组人群的相关精液指标稍优于20~25岁组;身高与各精液指标无关。职业对精液指标ALH没有影响(P=0.695/0.886),而对其他精液指标都有影响(P<0.01)。结论:年龄、职业对精液指标ALH没有影响,对其他精液指标都有一定的影响;身高对精液指标数值没有显著影响。

【Abstract】 Objective: To explore the correlation between the biological characteristics of volunteer donors and sperm parameters. Methods: Sperm parameters were analyzed for 778 primary volunteer donors by CASA system with standard methods recommended by WHO including sperm concentration,motility rate,VCL,VSL,ALH,LIN,STR and BCF,and their biological characteristics were recorded.Results: Of all the volunteer donors,students accounted for more than a third,(89.2) percent were under the age of 35 years,(71.6) percent between 166 and 175 cm in height,(91.7) percent of normal weight and(77.1) percent with college education.The median sperm concentration and motility rate were(107.00)×106/ml and 75 percent respectively.Age was weakly correlated with such semen indexes as concentration(r=(0.210),P=(0.000)),motility rate(r=(0.213),P=(0.000)),volume(r=(0.165),P=(0.002)),VAP(r=(0.259),P=(0.000)),VSL(r=(0.281),P=(0.000)),VCL(r=(0.190),P=(0.000)),BCF(r=(0.243),P=(0.000)) and LIN(r=(0.192),P=(0.000)).The semen indexes of the 26-35 age group were a little better than those of the 20-25.Height showed no correlation to semen indexes.Education and occupation were somewhat related with other sperm parameters(P<(0.01)) than ALH(P=(0.695)/(0.886)).Conclusion: Age,occupation and education bear some correlation with sperm parameters except ALH,while height has none with any of them.

【基金】 广东省科技攻关项目(2003B30606)
  • 【文献出处】 中华男科学杂志 ,National Journal of Andrology , 编辑部邮箱 ,2007年01期
  • 【分类号】R698.2
  • 【被引频次】1
  • 【下载频次】98
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