【摘要】 目的研究脂肪肝及脂肪性肝炎在武汉水果湖地区的流行趋势、现状与危险因素。方法回顾性收集武汉大学中南医院体检中心武汉市水果湖地区机关、学校、企业事业单位职员7247人,平均年龄(43.25±13.63)岁,男性4253人,女性2994人。测定体重指数、空腹血糖、丙氨酸氨基转移酶、胆固醇和甘油三脂等指标,并进行血压检测及腹部B超检查。结果武汉水果湖地区体检人员检出脂肪肝1779例(24.5%),其中男性1347例(75.7%),女性432例(24.3%)。脂肪肝随年龄上升而上升,男性50～60岁患病率最高,女性60～70岁最高。脂肪肝随体重指数上升而上升,超重者及肥胖者1584人(89.0%),其中肥胖者1226人(68.9%)。脂肪肝伴发高血压病者520例(29.2%),空腹血糖大于6.1mmol/L者447例(25.1%),高血脂症者1128例(63.4%)。脂肪性肝炎发病率为4.9%。结论城市脂肪肝发病率男性明显大于女性,60岁以后女性发病率大于男性。超重及肥胖、男性、增龄、高血压、高丙氨酸氨基转移酶、高脂血症、糖代谢紊乱等为脂肪肝危险因素。更多还原

【Abstract】 Objective To investigate the prevalence and risk factors of fatty liver in Shuiguohu district of Wuhan City.Method To survey retrospectively 7247 subjects lived in Shuiguohu district of Wuhan city in central China by random collection during a period from Mar.2003.3 to Apr. 2004.4. Height、weight、fasting blood sugar(FBS)、alanine aminotransferase(ALT)、total cholesterol(TC)、 triclyceride(TG) of the subjects and B ultrasound for abdomen were determined.Results 1779 (24.5%) cases of fatty liver were determined,1347 (75.7%) cases were male and 432(24.3%) cases were female.The fatty liver increases with age.The highest of male fatty liver is among 50-60 years old,and that of female is among 60-70 years old.The patients with fatty liver were also increased with body mass index (BMI).Among these fatty liver patients,1584(89.0%) cases were overweight and obese,520(29.2%) cases were associated with hypertension,447(25.1%) cases were associated with fasting hyperglycaemia and 1128(63.4%) cases were associated with dyslipidemia.The incidence of steatohepatitis is 4.9%.Conclusion The prevalence of fatty liver in Wuhan area,central China was 24.5%,and the risk factors for the fatty liver were associated with male,dyslipidemia、obesity、hypertension and fasting hyperglycaemia.更多还原