【摘要】 在氟化钾作用下,以四苯基溴化磷为催化剂,微波促进卤素交换制备了氟代芳香化合物。考察了不同溶剂,不同助催化剂对反应的影响并与常规加热的反应进行了对比。结果表明,在硝基苯溶剂中,n（氯代芳香化合物）:n（氟化钾）=1∶3、n（Ph₄PBr）∶n（氯代芳香化合物）=1∶10、n（冠醚）∶n（氯代芳香化合物）=1∶20,反应温度210℃条件下,合成了9种氟代芳香化合物,收率76%～92%,微波辅助反应比常规加热反应时间缩短2～3 h。更多还原

【Abstract】 The fluorobenzaldehydes were prepared through the catalysis of Ph₄PBr and KF under the irradiation of microwave.Nine fluorohenzaldehydes were prepared with the yields of 76%-92% under the following conditions:n（chlorobenzaldehyde）:n（KF）=1:3,n（Ph₄PBr）:n（chlorobenzalde- hyde）=1:10,n（crown ester）:n（chlorobenzaldehyde）=1:20 and reaction temperature 210℃.In comparison with oil heating,the reaction time could be shortened by more than 2-3 h,and the yields were increased by 3%-5% by the microwave irradiation.更多还原