【摘要】 目的了解无抽搐电休克治疗(MECT)对难治性精神分裂症(TRS)的疗效与不良反应。方法对78例TRS患者在原服用抗精神病药物基础上合并MECT治疗,分别于合并治疗前后采用阳性与阴性症状量表(PANSS)、副反应量表(TESS)、韦氏记忆量表(WMS)评定疗效及不良反应。结果合并MECT后省PANSS评分明显降低(P<0.01)WMS评分在治疗结束后1d明显降低,1周及2周时恢复。结论MECT对TRS有效,不良反应少。更多还原

【Abstract】 Objective To explore the efficacy and side effects of modified electroconvulsive therapy(MECT) in treatment-refractory schizophrenia.Methods 78 patients with TRS who had received antipsychotic medication were assigned to receive MECT, and the positive and negative syndrome scale(PANSS)、treatment emergent symptoms scale(TESS) and Wechsler memory scale(WMS)were used before and after treatment. Results The PANSS scores decreased significantly after MECT. The WMS scores decreased significantly at 1 day after the endpoint of MECT. but there were no significant difference between before and after 1、2weeks of endpoint of MECT. Conclusions Conclusions MECT was effective in TRS, and it had little side effects.更多还原